Description
2-Deoxy-D-glucose Chemical Properties
| Melting point | 146-147 °C(lit.) |
| alpha | 45.5 º (c=2, H2O) |
| Boiling point | 211.61°C (rough estimate) |
| density | 1.1738 (rough estimate) |
| refractive index | 46.5 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL, clear, colorless to faintly yellow |
| form | crystalline |
| pka | pK1:12.52 (25°C) |
| color | white |
| Water Solubility | Soluble in water. |
| Merck | 14,2904 |
| BRN | 1723331 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day. |
| InChIKey | PMMURAAUARKVCB-CEZCPVKQSA-N |
| LogP | -1.460 (est) |
| CAS DataBase Reference | 154-17-6(CAS DataBase Reference) |
| EPA Substance Registry System | D-arabino-Hexose, 2-deoxy- (154-17-6) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 24/25-37/39-36-26 |
| WGK Germany | 3 |
| RTECS | MQ3325000 |
| F | 3-10 |
| TSCA | Yes |
| HS Code | 29400090 |
| Hazardous Substances Data | 154-17-6(Hazardous Substances Data) |
Product Application of 2-Deoxy-D-glucose CAS#154-17-6
2-Deoxy-D-glucose is a derivative of D-glucose. It is an antimetabolite and an important component of the envelope of orthomyxovirus, paramyxovirus and herpes virus. It interferes with the synthesis of virus-specific glycoproteins and can effectively inhibit the proliferation of herpes simplex virus, RNA and DNA enveloped viruses, and breast cancer cells. Antiviral and anticancer drugs made from 2-deoxy-D-glucose have been used in clinical treatment research of herpes simplex virus, influenza, AIDS and cancer; anti-aging cosmetics and medical health products made from 2-deoxy-D-glucose are also on the market. Therefore, as a drug for treating cancer, viral diseases and anti-aging, 2-deoxy-D-glucose has broad application prospects and huge market demand.
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